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Acute bronchitis laboratory tests

Introduction

Overview

Overview

Diagnostic tests are rarely needed to confirm the diagnosis of acute bronchitis. In very specific conditions, serologic tests, viral cultures or sputum analyses may be applied. Generally, inflammatory markers such as CRP rise during the course of acute bronchitis.

Laboratory Tests

Laboratory Tests

  • Diagnostic tests are rarely needed to confirm the diagnosis of acute bronchitis.
  • Viral cultures, serologic assays, and sputum analyses may be perform when a potentially treatable infection is thought to be circulating or for epidemiological purposes.[1]

Serologic assays

Procalcitonin

  • Procalcitonin level is helpful to distinguish bacterial from other causes of inflammation. During bacterial infections, the level of procalcitonin will rise over 0.25 mg/L and indicates prescription of antibiotics.[2][3][4]
References

References

  1. ↑ 1.0 1.1 Wenzel RP, Fowler AA (2006). “Clinical practice. Acute bronchitis”. N. Engl. J. Med. 355 (20): 2125–30. doi:10.1056/NEJMcp061493. PMIDΒ 17108344.
  2. ↑ Schuetz P, Christ-Crain M, Thomann R, Falconnier C, Wolbers M, Widmer I, Neidert S, Fricker T, Blum C, Schild U, Regez K, Schoenenberger R, Henzen C, Bregenzer T, Hoess C, Krause M, Bucher HC, Zimmerli W, Mueller B (2009). “Effect of procalcitonin-based guidelines vs standard guidelines on antibiotic use in lower respiratory tract infections: the ProHOSP randomized controlled trial”. JAMA. 302 (10): 1059–66. doi:10.1001/jama.2009.1297. PMIDΒ 19738090.
  3. ↑ Briel M, Schuetz P, Mueller B, Young J, Schild U, Nusbaumer C, PΓ©riat P, Bucher HC, Christ-Crain M (2008). “Procalcitonin-guided antibiotic use vs a standard approach for acute respiratory tract infections in primary care”. Arch. Intern. Med. 168 (18): 2000–7, discussion 2007–8. doi:10.1001/archinte.168.18.2000. PMIDΒ 18852401.
  4. ↑ Gilbert DN (2011). “Procalcitonin as a biomarker in respiratory tract infection”. Clin. Infect. Dis. 52 Suppl 4: S346–50. doi:10.1093/cid/cir050. PMIDΒ 21460294.


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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Seyedmahdi Pahlavani, M.D. [2]; Nate Michalak, B.A.