Acute cholecystitis primary prevention

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Furqan M M. M.B.B.S [2]

Overview

Administration of NSAIDs in the patients with biliary colic prevents the progression to acute cholecystitis.

Primary Prevention

Administration of NSAIDs in the patients with biliary colic prevents the progression to acute cholecystitis.^[1]^[2]
- NSAIDs such as diclofenac or indomethacin is used in the patients with biliary colic for their analgesic effects and their inhibition of prostaglandin release from the gallbladder wall.
Administration of diclofenac (75 mg; intramuscular injection) in patients with biliary colic attack relieved the pain and prevented the progression of the disease to acute cholecystitis.^[2]

References

↑ Yoshida M, Takada T, Kawarada Y, Tanaka A, Nimura Y, Gomi H, Hirota M, Miura F, Wada K, Mayumi T, Solomkin JS, Strasberg S, Pitt HA, Belghiti J, de Santibanes E, Fan ST, Chen MF, Belli G, Hilvano SC, Kim SW, Ker CG (2007). “Antimicrobial therapy for acute cholecystitis: Tokyo Guidelines”. J Hepatobiliary Pancreat Surg. 14 (1): 83–90. doi:10.1007/s00534-006-1160-y. PMC 2784497. PMID 17252301.
↑ ^2.0 ^2.1 Akriviadis EA, Hatzigavriel M, Kapnias D, Kirimlidis J, Markantas A, Garyfallos A (1997). “Treatment of biliary colic with diclofenac: a randomized, double-blind, placebo-controlled study”. Gastroenterology. 113 (1): 225–31. PMID 9207282.

Overview