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Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

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Acute kidney injury epidemiology and demographics

Introduction

Overview

Overview

The incidence less severe AKI is approximately 200-300 per 100,000 individuals worldwide. The prevalence of acute kidney injury is approximately 400-500 per 100,000 individuals worldwide. Patients of all age groups may develop AKI. The incidence of AKI increases with age; the median age at diagnosis is 76 years. AKI affects men and women equally.

Epidemiology and Demographics

Epidemiology and Demographics

Incidence

  • The incidence less severe AKI is approximately 200-300 per 100,000 individuals worldwide.[1]
  • The incidence AKI treated with renal replacement therapy is approximately 20 to 30 per 100,000 individuals worldwide.
  • Ali et al reported a high incidence of 1811 cases of AKI per 1000,000 population during 2003.[2]

Prevalence

  • The prevalence of acute kidney injury is approximately 400-500 per 100,000 individuals worldwide.

Case-fatality rate/Mortality rate

  • In 2005, the mortality among patients with severe AKI requiring renal replacement therapy was 60.3%.

Age

  • Patients of all age groups may develop AKI.
  • The incidence of AKI increases with age; the median age at diagnosis is 76 years.
  • Chronic renal failure is usually first diagnosed among patients with 80 years old.

Race

  • AKI usually affects individuals of the African America race. Caucasians individuals are less likely to develop AKI.[3]

Gender

  • AKI affects men and women equally.[4]
References

References

  1. ↑ Hoste EA, Schurgers M (April 2008). “Epidemiology of acute kidney injury: how big is the problem?”. Crit. Care Med. 36 (4 Suppl): S146–51. doi:10.1097/CCM.0b013e318168c590. PMID 18382186.
  2. ↑ Ali T, Khan I, Simpson W, Prescott G, Townend J, Smith W, Macleod A (April 2007). “Incidence and outcomes in acute kidney injury: a comprehensive population-based study”. J. Am. Soc. Nephrol. 18 (4): 1292–8. doi:10.1681/ASN.2006070756. PMID 17314324.
  3. ↑ Grams ME, Matsushita K, Sang Y, Estrella MM, Foster MC, Tin A, Kao WH, Coresh J (August 2014). “Explaining the racial difference in AKI incidence”. J. Am. Soc. Nephrol. 25 (8): 1834–41. doi:10.1681/ASN.2013080867. PMC 4116065. PMID 24722442.
  4. ↑ Lima-Posada I, Portas-Cortés C, Pérez-Villalva R, Fontana F, Rodríguez-Romo R, Prieto R, Sánchez-Navarro A, Rodríguez-González GL, Gamba G, Zambrano E, Bobadilla NA (September 2017). “Gender Differences in the Acute Kidney Injury to Chronic Kidney Disease Transition”. Sci Rep. 7 (1): 12270. doi:10.1038/s41598-017-09630-2. PMC 5612964. PMID 28947737.

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Farima Kahe M.D. [2]