Health Dictionary
Reliable, easy-to-read patient information on common medical conditions โ written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Acute retinal necrosis causes
Introduction
Overview
Overview
Acute retinal necrosis is usually caused by reactivation of latent viruses, including Herpes simplex virus 1 & 2, Varicella-zoster virus, cytomegalovirus, and Epstein-Barr virus.
Causes
Causes
Acute retinal necrosis (ARN) is usually caused by the reactivation of the following pathogenic viruses in the Herpesviridae family:[1][2][3][4][5][6]
- Herpes simplex virus 1 (HSV-1)
- Herpes simplex virus 2 (HSV-2)
- Varicella-zoster virus (VZV)
- Less commonly, ARN can be caused by Epstein-Barr virus and cytomegalovirus.[5][7][8]
- VZV and HSV-1 are usually the causes of ARN in individuals older than 25 years.
- The majority of the ARN cases for individuals older than 50 years are caused by VZV and HSV-1.[9]
HSV-2 is usually the cause of ARN in individuals younger than 25 years.
References
References
- โ Pikkel YY, Pikkel J (2014). “Acute retinal necrosis in childhood”. Case Rep Ophthalmol. 5 (2): 138โ43. doi:10.1159/000363130. PMCย 4049010. PMIDย 24932179.
- โ Kawaguchi T, Spencer DB, Mochizuki M (2008). “Therapy for acute retinal necrosis”. Semin Ophthalmol. 23 (4): 285โ90. doi:10.1080/08820530802111192. PMIDย 18584565.
- โ Usui Y, Goto H (2008). “Overview and diagnosis of acute retinal necrosis syndrome”. Semin Ophthalmol. 23 (4): 275โ83. doi:10.1080/08820530802111325. PMIDย 18584564.
- โ Kezuka T, Atherton SS (2007). “Acute retinal necrosis”. Chem Immunol Allergy. 92: 244โ53. doi:10.1159/000099275. PMIDย 17264500.
- โ 5.0 5.1 Bonfioli AA, Eller AW (2005). “Acute retinal necrosis”. Semin Ophthalmol. 20 (3): 155โ60. doi:10.1080/08820530500232027. PMIDย 16282149.
- โ Chun HL, Missotten T, Salzmann J, Lightman SL (2007). “Acute Retinal Necrosis: Features, Management, and Outcomes”. Opthalmology. 114: 756โ762. Unknown parameter
|Issue=ignored (|issue=suggested) (help) - โ Ganatra JB, Chandler D, Santos C, Kuppermann B, Margolis TP (2000). “Viral causes of the acute retinal necrosis syndrome”. Am. J. Ophthalmol. 129 (2): 166โ72. PMIDย 10682968.
- โ Gartry DS, Spalton DJ, Tilzey A, Hykin PG (1991). “Acute retinal necrosis syndrome”. Br J Ophthalmol. 75 (5): 292โ7. PMCย 1042358. PMIDย 1645179.
- โ Brydak-Godowska J, Borkowski P, Szczepanik S, Moneta-Wielgoล J, Kฤcik D (2014). “Clinical manifestation of self-limiting acute retinal necrosis”. Med. Sci. Monit. 20: 2088โ96. doi:10.12659/MSM.890469. PMCย 4226315. PMIDย 25356955.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Luke Rusowicz-Orazem, B.S.