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Reliable, easy-to-read patient information on common medical conditions โ written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Acute retinal necrosis epidemiology and demographics
Introduction
Overview
Overview
The estimated incidence of acute retinal necrosis (ARN) is approximately 6.3 per 100,000 individuals. ARN that has developed from Herpes simplex virus 1 or Varicella-zoster virus is most common among patients older than 50 years, while the incidence of HSV-2 caused ARN is highest in children and young adults between age 9 and 22 years. There is no racial or gender predisposition to acute retinal necrosis.
Epidemiology and Demographics
Epidemiology and Demographics
Incidence
- The estimated incidence of ARN is approximately 6.3 per 100,000 individuals.
- Worldwide, the increase in immunocompromised and aged populations in most countries has been correlated with an increase in the incidence of acute retinal necrosis.[1]
- There is evidence that this incidence is underestimated due to biases in case adjudication and under-reporting of data.[2][3][4][5][6]
Age
- Acute retinal necrosis (ARN) developed from Herpes simplex virus 1 and Varicella-zoster virus is most common among patients older than 50 years.[7]
- Herpes simplex virus (HSV) 2 infection is more common among children and adolescents; the incidence of HSV-2-caused ARN is highest in children and young adults between age 9 and 22 years.
Gender
There is no gender predisposition to acute retinal necrosis.
Race
There is no racial predisposition to acute retinal necrosis.
References
References
- โ Cochrane TF, Silvestri G, McDowell C, Foot B, McAvoy CE (2012). “Acute retinal necrosis in the United Kingdom: results of a prospective surveillance study”. Eye (Lond). 26 (3): 370โ7, quiz 378. doi:10.1038/eye.2011.338. PMCย 3298997. PMIDย 22281865.
- โ Muthiah MN, Michaelides M, Child CS, Mitchell SM (2007). “Acute retinal necrosis: a national population-based study to assess the incidence, methods of diagnosis, treatment strategies and outcomes in the UK”. Br J Ophthalmol. 91 (11): 1452โ5. doi:10.1136/bjo.2007.114884. PMCย 2095441. PMIDย 17504853.
- โ Usui Y, Goto H (2008). “Overview and diagnosis of acute retinal necrosis syndrome”. Semin Ophthalmol. 23 (4): 275โ83. doi:10.1080/08820530802111325. PMIDย 18584564.
- โ Kezuka T, Atherton SS (2007). “Acute retinal necrosis”. Chem Immunol Allergy. 92: 244โ53. doi:10.1159/000099275. PMIDย 17264500.
- โ Bonfioli AA, Eller AW (2005). “Acute retinal necrosis”. Semin Ophthalmol. 20 (3): 155โ60. doi:10.1080/08820530500232027. PMIDย 16282149.
- โ Chun HL, Missotten T, Salzmann J, Lightman SL (2007). “Acute Retinal Necrosis: Features, Management, and Outcomes”. Opthalmology. 114: 756โ762. Unknown parameter
|Issue=ignored (|issue=suggested) (help) - โ Brydak-Godowska J, Borkowski P, Szczepanik S, Moneta-Wielgoล J, Kฤcik D (2014). “Clinical manifestation of self-limiting acute retinal necrosis”. Med. Sci. Monit. 20: 2088โ96. doi:10.12659/MSM.890469. PMCย 4226315. PMIDย 25356955.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Luke Rusowicz-Orazem, B.S.