Acute tubular necrosis epidemiology and demographics

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Chandrakala Yannam, MD [2]

Overview

Incidence of acute tubular necrosis is approximately 88 per 100,000 individuals worldwide. The mean age at diagnosis of acute tubular necrosis was 59.5 years. Mortality rate is high with acute tubular necrosis among hospitalized and ICU patients. Acute tubular necrosis affects men and women equally.

Epidemiology and Demographics

Incidence

The incidence of acute tubular necrosis is approximately 88 cases per 100,000 individuals.^[1]
- The incidence of acute tubular necrosis due to renal ischemia is approximately 12.7 cases per 100,000 individuals.^[2]
- The incidence of acute tubular necrosis due to sepsis is approximately 24.7 cases per 100,000 individuals.
- The incidence of acute tubular necrosis due to rhabdomyolysis and nephrotoxic medications is approximately 10.7 cases and 7.3 cases per 100,000 individuals.

Prevalence

The prevalence of acute tubular necrosis is not known.
Renal ischemia leading acute tubular necrosis and acute kidney injury is the most common cause of acute tubular necrosis.

Case-fatality rate/Mortality rate

The case-fatality rate/mortality rate of acute tubular necrosis is approximately 37% among hospitalized individuals.

Age

Patients of all age groups may deveolp acute tubular necrosis.
The mean age at diagnosis of acute tubular necrosis was 59.5 years.

Race

There is no racial predilection to acute tubular necrosis.

Gender

Acute tubular necrosis affects men and woman equally.

Region

There is no specific regional distribution to acute tubular necrosis.

References

↑ Liaño F, Pascual J (September 1996). “Epidemiology of acute renal failure: a prospective, multicenter, community-based study. Madrid Acute Renal Failure Study Group”. Kidney Int. 50 (3): 811–8. PMID 8872955.
↑ Al-Homrany M (2003). “Epidemiology of acute renal failure in hospitalized patients: experience from southern Saudi Arabia”. East. Mediterr. Health J. 9 (5–6): 1061–7. PMID 16450538.

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[pmid8872955-1] Liaño F, Pascual J (September 1996). “Epidemiology of acute renal failure: a prospective, multicenter, community-based study. Madrid Acute Renal Failure Study Group”. Kidney Int. 50 (3): 811–8. PMID 8872955.

[pmid16450538-2] Al-Homrany M (2003). “Epidemiology of acute renal failure in hospitalized patients: experience from southern Saudi Arabia”. East. Mediterr. Health J. 9 (5–6): 1061–7. PMID 16450538.

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