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Addison's disease historical perspective

Introduction

Overview

Overview

Addison’s disease is named after Dr. Thomas Addison, a British physician who first described the condition in his paper “On the Constitutional and Local Effects of Disease of the Suprarenal Capsules” in 1855.[1][2]

Historical perspective

Historical perspective

  • In 1563, Bartholomeus Eustachius, an anatomy professor at the Collegio della Sapienza in Rome was the first to give a description of the adrenal glands in his publication “glandulae renibus incumbentes”.
  • In 1586, Piccolomini was the first to name the glands as suprarenals.
  • In 1651, Highmore was the first to suggest that the suprarenals act to absorb exudates from the large vessels.
  • In 1656, Thomas Wharton was the first to describe the concept of the neuroendocrine function of the adrenal medulla.
  • In 1805, Cuvier was the first to give a detailed description of medulla and cortex of adrenal glands.
  • In 1852, Albert von Kölliker was the first to give a detailed microscopic description of the adrenal glands.
  • In 1855, Thomas Addison was the first to identify and name Addison’s disease in his paper “On the Constitutional and Local Effects of Disease of the Suprarenal Capsules”.
  • In 1856, Charles Brown-Séquard provided experimental proof of the vital role of the adrenals by performing adrenalectomies (the removal of adrenals) from several animal species.
References

References

  1. ↑ Thomas Addison. On The Constitutional And Local Effects Of Disease Of The Supra-Renal Capsules (HTML reprint). London: Samuel Highley.
  2. ↑ Ten S, New M, Maclaren N (2001). “Clinical review 130: Addison’s disease 2001”. J. Clin. Endocrinol. Metab. 86 (7): 2909–22. PMID 11443143.

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Aditya Ganti M.B.B.S. [2]