The symptoms of adiposogenital dystrophy are due to deficiency of hypothalamic and pituitary hormones. The condition will not improve without treatment and often worsens over time.

Patients develop prepubertal obesity with fat deposition at the breasts, hips, femoral regions, and abdomen, Dehydration and hypernatremia can occur as a result of antidiuretic hormone deficiency. Mental retardation may also be seen^[1]. Radiologic findings include delayed bone ossification. If a pituitary tumor is involved, there may also be visual disturbances, which may be seen with or without compression of the optic chiasm ^{[2] [3]}.

Complications of adiposogenital syndrome include^[4][5]:

• Obesity which can further lead to a variety of health conditions
• Mental retardation which has socioeconomic impact on the patient, the patient’s family, and the society
• Diabetes insipidus which may lead to dehydration, electrolyte imbalance, organ dysfunction and death
• Short stature
• Infertility
• Osteoporosis and an increased risk of fractures

Prognosis depends on the underlying cause. Without treatment, there is no improvement in the condition. Radiation and surgical removal of tumors may aid in treatment. Hormone replacement for the hormones that are underproduced as well as diet and exercise are important in the management of the condition^[6].

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