Adrenal insufficiency history and symptoms

The hallmark of adrenal insufficiency is fatigue. Most patients with adrenal insufficiency present with non specific symptoms. A positive history of fatigue,nausea and abdominal pain is suggestive of adrenal insufficiency. The most common symptoms of adrenal insufficiency include fatigue, anorexia, and weight loss. Common symptoms of adrenal insufficiency include abdominal pain, nausea, and vomiting. Less common symptoms of adrenal insufficiency include diarrhea, arthralgia, and myalgia. ^[1][2]

• The hallmark of adrenal insufficiency is fatigue. Most patients present with nonspecific symptoms making the diagnosis difficult. The most common symptoms of adrenal insufficiency include fatigue, anorexia, and weight loss.^{[1] [2]}

Patients with adrenal insufficiency may have a positive history of:

• Fatigue
• Nausea
• Abdominal pain

Common symptoms of adrenal insufficiency include:

• Fatigue
• Anorexia
• Weight loss
• Abdominal pain
• Nausea
• Vomiting
• Lethargy

Less common symptoms of adrenal insufficiency include:

• Diarrhea
• Arthralgia
• Myalgia

Patients with Primary adrenal insufficiency present with additional symptoms of:

• Postural dizziness
• Muscle cramps
• Salt craving

Patients with glucocorticoid-induced adrenal insufficiency may initially develop signs and symptoms of Cushing syndrome, such as weight gain, central obesity, sarcopenia with proximal muscle weakness, skin fragility, and easy bruising due to treatment with supraphysiological doses of glucocorticoids ^[3].

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