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Health Dictionary

Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

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Adrenocortical carcinoma laboratory findings

Introduction

Overview

Overview

Patients with functional adrenocortical carcinoma may have elevated concentrations of serum cortisol, aldosterone, testosterone or estrogen and reduced concentration of plasma renin and potassium.

Laboratory Findings

Laboratory Findings

Laboratory findings consistent with adrenocortical carcinoma are:

Hormonal disturbance labs
Cortisol[1]
Steroids[2]
Epinephrine[3]
Aldosterone[4]
  • Low serum aldosterone concentrations, normal or high serum or urinary concentrations of aldosterone precursors
References

References

  1. ↑ Dunlap NE, Grizzle WE, Siegel AL (1985). “Cushing’s syndrome. Screening methods in hospitalized patients”. Arch Pathol Lab Med. 109 (3): 222–9. PMID 3838451.
  2. ↑ Fassnacht M, Allolio B (2009). “Clinical management of adrenocortical carcinoma”. Best Pract Res Clin Endocrinol Metab. 23 (2): 273–89. doi:10.1016/j.beem.2008.10.008. PMID 19500769.
  3. ↑ Song G, Joe BN, Yeh BM, Meng MV, Westphalen AC, Coakley FV (2011). “Risk of catecholamine crisis in patients undergoing resection of unsuspected pheochromocytoma”. Int Braz J Urol. 37 (1): 35–40, discussion 40-1. PMID 21385478.
  4. ↑ Arlt W, Biehl M, Taylor AE, Hahner S, Libé R, Hughes BA; et al. (2011). “Urine steroid metabolomics as a biomarker tool for detecting malignancy in adrenal tumors”. J Clin Endocrinol Metab. 96 (12): 3775–84. doi:10.1210/jc.2011-1565. PMC 3232629. PMID 21917861.

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmad Al Maradni, M.D. [2] Mohammed Abdelwahed M.D[3]