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Adrenomyeloneuropathy

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

Overview

Adrenomyeloneuropathy is a rare inherited disorder. It is a form of X-linked adrenoleukodystrophy. Leukodystrophy causes a disruption to the myelin sheath that covers and protects nerves. Prognosis is normally poor and death usually occurs within a few years after onset.

Historical Perspective

Historical Perspective

Classification

Classification

Pathophysiology

Pathophysiology

Causes

Causes

Differentiating Adrenomyeloneuropathy from Other Diseases

Differentiating Adrenomyeloneuropathy from Other Diseases

Epidemiology and Demographics

Epidemiology and Demographics

Risk Factors

Risk Factors

Screening

Screening

Natural History, Complications, and Prognosis

Natural History, Complications, and Prognosis

Diagnosis

Diagnosis

Diagnostic Criteria

History and Symptoms

Physical Examination

Laboratory Findings

Imaging Findings

Other Diagnostic Studies

Treatment

Treatment

Medical Therapy

Surgery

Prevention

Other Sources

Other Sources

References

References

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