Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Adult T-cell leukemia laboratory findings
Introduction
Overview
Overview
Laboratory findings consistent with the diagnosis of adult T-cell leukemia include abnormal anemia, thrombocytopenia, and elevated lymphocyte count. Hypercalcemia is a key feature among patients with adult T-cell leukemia.
Laboratory Findings
Laboratory Findings
The following laboratory abnormalities may be observed in patients suffering from adult T-cell leukemia:[1][2][3]
Complete Blood Count
- Anemia
- Thrombocytopenia
- Elevated lymphocyte count
Basic Metabolic Panel
Peripheral Smear
- Characteristic leukemia cells with sharp nuclear indentations and a prominent nucleoli
- “Cloverleaf” or “flower” cells
Antibody Titres
- Detects antibodies present against HTLV antigens
Immunohistochemistry
References
References
- ↑ Matutes E (2007) Adult T-cell leukaemia/lymphoma. J Clin Pathol 60 (12):1373-7. DOI:10.1136/jcp.2007.052456 PMID: 18042693
- ↑ Shimoyama M (1991). “Diagnostic criteria and classification of clinical subtypes of adult T-cell leukaemia-lymphoma. A report from the Lymphoma Study Group (1984-87)”. Br J Haematol. 79 (3): 428–37. PMID 1751370.
- ↑ Mahieux R, Gessain A (2007). “Adult T-cell leukemia/lymphoma and HTLV-1”. Curr Hematol Malig Rep. 2 (4): 257–64. doi:10.1007/s11899-007-0035-x. PMID 20425378.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2]; Grammar Reviewer: Natalie Harpenau, B.S.[3]