Affective spectrum
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Overview
The affective spectrum is a grouping of related psychiatric and medical disorders which may accompany bipolar, unipolar, and schizoaffective disorders at statistically higher rates than would normally be expected. These disorders are identified by a common positive response to the same types of pharmacologic treatments. They also aggregate strongly in families and may therefore share common heritable underlying physiologic anomalies.
Affective spectrum disorders include:
- Attention-deficit hyperactivity disorder
- Bipolar disorder
- Body dysmorphic disorder
- Bulimia nervosa and other eating disorders
- Cataplexy
- Dysthymia
- General anxiety disorder
- Hypersexuality
- Impulse-control disorders
- Kleptomania
- Migraine
- Major Depressive Disorder
- Narcolepsy
- Obsessive-compulsive disorder
- Panic disorder
- Posttraumatic stress disorder
- Premenstrual dysphoric disorder
- Social phobia
The following may also be part of the spectrum accompanying affective disorders.
- Chronic pain
- Intermittent explosive disorder
- Pathological gambling
- Personality disorder
- Pyromania
- Substance abuse and addiction (includes alcoholism)
- Trichotillomania
Also, there are now studies linking heart disease.
Please note that many of the terms above overlap. The generally accepted definition of these terms can be found in the Diagnostic and Statistical Manual of Mental Disorders (DSM).
References
References
Hudson J.I., Pope H.G., Jr. (1990). “Affective spectrum disorder: does antidepressant response identify a family of disorders with a common pathophysiology?” Am Journal of Psychiatry. 147(5):552-64. (PMID 2183630).
Hudson J.I., Mangweth B., Pope H.G., Jr., De Col C., Hausmann A., Gutweniger S., Laird N.M., Biebl W., Tsuang M.T. (2003). “Family study of affective spectrum disorder”. Arch Gen Psychiatry. 60(2):170-7. (PMID 12578434).
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