Alcoholic hepatitis other diagnostic studies

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Shadan Mehraban, M.D.[2]

Overview

Liver biopsy is indicated in patients whose diagnosis is uncertain and in patients with severe Alcoholic Hepatitis who are probable to undergo medical treatment. Liver biopsy in Alcoholic Hepatitis include Polymorphonuclear infiltration, hepatic necrosis, Mallory bodies in hepatocytes, perivenular and perisinusoidal fibrosis, ballooning hepatocytes, and steatosis.

Other Diagnostic Studies

Liver biopsy is indicated in patients whose diagnosis is uncertain and in patients with severe Alcoholic Hepatitis who are probable to undergo medical treatment.^[1]
Findings of liver biopsy in Alcoholic Hepatitis include:^[2]^[3]
- Polymorphonuclear infiltration
- Hepatic necrosis
- Mallory bodies in hepatocytes
- Perivenular and perisinusoidal fibrosis
- Ballooning hepatocytes
- Steatosis

References

↑ O’Shea RS, Dasarathy S, McCullough AJ, Practice Guideline Committee of the American Association for the Study of Liver Diseases. Practice Parameters Committee of the American College of Gastroenterology (2010). “Alcoholic liver disease”. Hepatology. 51 (1): 307–28. doi:10.1002/hep.23258. PMID 20034030.
↑ “Alcoholic liver disease: morphological manifestations. Review by an international group”. Lancet. 1 (8222): 707–11. 1981. PMID 6110925.
↑ Elphick DA, Dube AK, McFarlane E, Jones J, Gleeson D (2007). “Spectrum of liver histology in presumed decompensated alcoholic liver disease”. Am J Gastroenterol. 102 (4): 780–8. doi:10.1111/j.1572-0241.2006.01034.x. PMID 17222323.

Overview