Alcoholic liver disease historical perspective

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: M. Khurram Afzal, MD [2]

Overview

Alcohol has existed as the most abused substance for many centuries. In 1960 alcohol was recognized as a hepatotoxin.

Historical Perspective

Alcohol has existed as the most abused substance for many centuries.^[1]
In 1960 alcohol was recognized as a hepatotoxin.
The earliest lesion reported for alcoholic liver disease is alcoholic steatosis (fatty liver).

References

↑ Rubin E, Lieber CS (1975). “Relation of alcoholic liver injury to cirrhosis”. Clin Gastroenterol. 4 (2): 247–72. PMID 47793.

Overview