Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Aldolase-B
Introduction
Aldolase B is an isoenzyme of fructose 1,6-bisphosphate aldolase (aldolase A), which is also capable of cleaving fructose 1-phosphate to form glyceraldehyde and dihydroxyacetone phosphate (DHAP). The reaction is reversible. Also known as Aldolase (Class II), it is found in the liver and kidney.
Pathology
Pathology
Defects of aldolase B cause fructose 1-phosphate to accumulate in tissues which contain fructokinase, a condition known as hereditary fructose intolerance.
External links
External links
- Aldolase+B at the US National Library of Medicine Medical Subject Headings (MeSH)