Aldolase-B
Aldolase B is an isoenzyme of fructose 1,6-bisphosphate aldolase (aldolase A), which is also capable of cleaving fructose 1-phosphate to form glyceraldehyde and dihydroxyacetone phosphate (DHAP). The reaction is reversible. Also known as Aldolase (Class II), it is found in the liver and kidney.
Pathology
Pathology
Defects of aldolase B cause fructose 1-phosphate to accumulate in tissues which contain fructokinase, a condition known as hereditary fructose intolerance.
External links
External links
- Aldolase+B at the US National Library of Medicine Medical Subject Headings (MeSH)
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