
Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Alpha-GPC
Introduction
Overview
Overview
L-Alpha Glycerylphosphorylcholine (Alpha GPC) is a naturally occurring phospholipid precursor and metabolite. Alpha GPC delivers choline to the brain across the blood-brain barrier.
Studies have investigated its efficacy for cognitive disorders including stroke and Alzheimer’s Disease. An Italian multicentre clinical trial on 2,044 patients suffering from recent stroke were supplied alpha-GPC in doses of 1,000 mg/day for 28 days and 400 mg/day for five ensuing months. The trial confirmed the therapeutic role of alpha-GPC on the cognitive recovery of patients based on four measurement scales, three of which reached statistical significance.[1]
References
References
- ↑ Barbagallo Sangiorgi G, et al. “Alpha-Glycerophosphocholine in the mental recovery of cerebral ischemic attacks.” An Italian multicenter clinical trial. Ann NY Acad Sci 1994; 717:253-69.
