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Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

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Aminoadipate-semialdehyde dehydrogenase

Introduction

Aminoadipate-semialdehyde dehydrogenase is a protein that in humans is encoded by the AASDH gene. [1]

Function

Function

This gene encodes a member of the non-ribosome peptide syntesase (NRPS) enzyme family. The encoded protein contains an AMP-binding domain, PP-binding (phosphopantetheine, or pantetheine 4’phosphate-binding) domain and the Pyrrolo-quinoline quinon (PQQ) binding domain. The protein is expressed in several adult tissues.

References

References

  1. ↑ “Entrez Gene: Aminoadipate-semialdehyde dehydrogenase”. Retrieved 2017-01-02.
Further reading

Further reading

  • Wang L, Jil C, Xu Y, Xu J, Dai J, Wu Q, Wu M, Zou X, Sun L, Gu S, Xie Y, Mao Y (2005). “Cloning and characterization of a novel human homolog* of mouse U26, a putative PQQ-dependent AAS dehydrogenase”. Mol. Biol. Rep. 32 (1): 47–53. PMID 15865210.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.