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Reliable, easy-to-read patient information on common medical conditions β€” written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

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Aminopropionitrile

Introduction

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Overview

Overview

Aminopropionitrile, also known as Ξ²-aminopropionitrile (BAPN), is an organic compound with both amine and nitrile functional groups. It is an antirheumatic agent in veterinary medicine. It can cause osteolathyrism, neurolathyrism, and/or angiolathyrism.[2]

Aminopropionitrile is prepared by the reaction of ammonia with acrylonitrile.[3]

BAPN is a component of lathyrus odoratus.[4]

See also

See also

References

References

  1. ↑ “Aminopropionitrile – Compound Summary”. PubChem Compound. USA: National Center for Biotechnology Information. 25 March 2005. Retrieved 7 June 2012.
  2. ↑ Nikolaos Papadantonakis, Shinobu Matsuura, and Katya Ravid. “Megakaryocyte pathology and bone marrow fibrosis: the lysyl oxidase connection”. Blood. 120 (9): 1774–1781. doi:10.1182/blood-2012-02-402594. BAPN is a lathyrogen, the toxic constituent of peas from Lathyrus plants. Lathyrism, a disease known for centuries, encompasses 2 distinct entities: a disorder of the nervous system (neurolathyrism) leading to limb paralysis, and a disorder of connective tissue, causing either bone deformity (osteolathyrism) or aortic aneurisms (angiolathyrim). BAPN causes osteolathyrism and angiolathyrism when ingested in large quantities.
  3. ↑ Karsten Eller, Erhard Henkes, Roland Rossbacher, Hartmut HΓΆke “Amines, Aliphatic” in Ullmann’s Encyclopedia of Industrial Chemistry, Wiley-VCH, Weinheim, 2005. doi:10.1002/14356007.a02_001
  4. ↑ “Lathyrus”. Washington, DC: American Association for Clinical Chemistry. 2014. Retrieved 15 October 2014. Beta-amino-propionitrile (BAPN) found in lathyrus odoratus (our more common garden sweet pea plant) is thought to be responsible for osteolathyrism, which in humans is quite poorly documented.

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]