Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Aminopterin fetopathy
Introduction
Synonyms and keywords: Aminopterin embryopathy syndrome, aminopterin fetopathy syndrome, aminopterin syndrome, aminopterin fetopathy
Overview
Overview
Congenital abnormalities have been documented with methotrexate and aminopterin, and collectively their teratogenic effects have become known as the fetal aminopterin syndrome.
Diagnosis
Diagnosis
History
A directed history should be obtained to ascertain prenatal exposure of methotrexate and aminopterin.
Physical Examination
Head
- Craniosynostosis – some or all of the sutures in the skull of an infant or child close too early, causing problems with normal brain and skull growth.
Ear
Extremities
Neurologic
References
References
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Kalsang Dolma, M.B.B.S.[2]