Anal dysplasia

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Anal dysplasia is a pre-cancerous condition which occurs when the lining of the anal canal undergoes abnormal changes. It can be classified as low-grade squamous intraepithelial lesions (LSIL) and high-grade squamous intraepithelial lesions (HSIL) ^[1] Most cases are not associated with symptoms, but people may notice lumps in and around the anus.^[2]^{broken link}

Causes

Anal dysplasia is most commonly linked to human papillomavirus (HPV), a usually sexually-transmitted infection.^[3] HPV is the most common sexually transmitted infection.^[4]

References

↑ Darragh, Teresa (October 2012). “The Lower Anogenital Squamous Terminology. Standardization Project for HPV-Associated Lesions:”. Arch Pathol Lab Med. 136: 1266-1297.
↑ Salit, Irving. “Fact Sheets: Anal dyspasia”. Canadian Aids Treatment Information Exchange. Retrieved 2009-02-22.
↑ Palefsky, Joel M.; Holly, Elizabeth A.; Ralston, Mary L.; Jay, Naomi (February 1988). “Prevalence and Risk Factors for Human Papillomavirus Infection of the Anal Canal in Human Immunodeﬁciency Virus (HIV)–Positive and HIV-Negative Homosexual Men” (PDF). Departments of Laboratory Medicine, Stomatology, and Epidemiology Biostatistics, University of California, San Francisco. The Journal of Infectious Diseases Oxford University Press. Retrieved 2 March 2014.
↑ “CDC Fact Sheet – Incidence, Prevalence, and Cost of Sexually Transmitted Infections in the United States” (PDF). CDC. February 2013. Retrieved 2 March 2014.

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[1] Darragh, Teresa (October 2012). “The Lower Anogenital Squamous Terminology. Standardization Project for HPV-Associated Lesions:”. Arch Pathol Lab Med. 136: 1266-1297.

[factsheetaids-2] Salit, Irving. “Fact Sheets: Anal dyspasia”. Canadian Aids Treatment Information Exchange. Retrieved 2009-02-22.

[3] Palefsky, Joel M.; Holly, Elizabeth A.; Ralston, Mary L.; Jay, Naomi (February 1988). “Prevalence and Risk Factors for Human Papillomavirus Infection of the Anal Canal in Human Immunodeﬁciency Virus (HIV)–Positive and HIV-Negative Homosexual Men” (PDF). Departments of Laboratory Medicine, Stomatology, and Epidemiology Biostatistics, University of California, San Francisco. The Journal of Infectious Diseases Oxford University Press. Retrieved 2 March 2014.

[4] “CDC Fact Sheet – Incidence, Prevalence, and Cost of Sexually Transmitted Infections in the United States” (PDF). CDC. February 2013. Retrieved 2 March 2014.

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Anal dysplasia

Overview

Causes

See also

References

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