Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Analgesic nephropathy diagnostic study of choice
Introduction
Overview
Overview
Renal biopsy is the diagnostic study of choice, however, since it is an invasive procedure, CT scan without contrast of the abdomen is usually preferred.
Diagnostic Study of Choice
Diagnostic Study of Choice
Renal Biopsy
- Renal biopsy is the diagnostic study of choice.[1]
- However, renal biopsy is an invasive procedure and there is risk of complications, therefore CT scan without contrast of the abdomen is usually preferred.[1][2]
- The pathology of classic analgesic nephropathy caused by phenacetin and phenacetin-containing analgesics was caused by capillary sclerosis in the renal medulla due to toxic metabolites of phenacetin which would lead to:[3][4]
- Papillary necrosis
- Tubulointerstitial nephropathy
- Cortical atrophy
References
References
- ↑ 1.0 1.1 “Analgesic Nephropathy – StatPearls – NCBI Bookshelf”.
- ↑ de Broe ME, Elseviers MM (1998). “Analgesic nephropathy”. N. Engl. J. Med. 338 (7): 446–52. PMID 9459649. Unknown parameter
|month=ignored (help) - ↑ Mihatsch MJ, Hofer HO, Gudat F, Knüsli C, Torhorst J, Zollinger HU (1983). “Capillary sclerosis of the urinary tract and analgesic nephropathy”. Clin Nephrol. 20 (6): 285–301. PMID 6641031.
- ↑ Mihatsch MJ, Khanlari B, Brunner FP (2006). “Obituary to analgesic nephropathy–an autopsy study”. Nephrol Dial Transplant. 21 (11): 3139–45. doi:10.1093/ndt/gfl390. PMID 16891638.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Shakiba Hassanzadeh, MD[2]