Anaphylaxis epidemiology and demographics

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1], Associate Editor(s)-in-Chief: Dushka Riaz, MD

Epidemiology and Demographics

Prevalence

In 2006, the lifetime prevalence of Anaphylaxis was estimated to be 0.05% to 2% in the United States. However it is believed that this is an underestimation because the disease is underdiagnosed. ^[1]

Case-fatality rate/Mortality rate

The mortality rate of Anaphylaxis is approximately 186 to 225 deaths/year. ^[2]

Age

Patients of all age groups may develop anaphylaxis, however, children and adolescents account for the majority of cases.^[3]

Race

There is no racial predilection to anaphylaxis.

Gender

Anaphylaxis affects men and women equally with more women being admitted to the hospital for the disease. ^[1]

Region

There is no regional predilection to anaphylaxis.

Developed Countries

An estimated 1.24% to 16.8% of the United States population is considered at risk for developing anaphylaxis if they are exposed to one or more allergens. Anaphylaxis results in fewer than 1,000 deaths per year in the U.S and the most common presentation is cardiovascular collapse ^[4] ^[5]

References

↑ ^1.0 ^1.1 LoVerde D, Iweala OI, Eginli A, Krishnaswamy G (2018). “Anaphylaxis”. Chest. 153 (2): 528–543. doi:10.1016/j.chest.2017.07.033. PMC 6026262. PMID 28800865.
↑ Ma L, Danoff TM, Borish L (2014). “Case fatality and population mortality associated with anaphylaxis in the United States”. J Allergy Clin Immunol. 133 (4): 1075–83. doi:10.1016/j.jaci.2013.10.029. PMC 3972293. PMID 24332862.
↑ Lieberman P, Camargo CA, Bohlke K, Jick H, Miller RL, Sheikh A; et al. (2006). “Epidemiology of anaphylaxis: findings of the American College of Allergy, Asthma and Immunology Epidemiology of Anaphylaxis Working Group”. Ann Allergy Asthma Immunol. 97 (5): 596–602. doi:10.1016/S1081-1206(10)61086-1. PMID 17165265.
↑ Neugut, Alfred, Anita Ghatak and Rachel Miller. “Anaphylaxis in the United States: An Investigation Into Its Epidemiology.” Arch Intern Med. 161.108 January 2001 15-21. 29 January 2007 <http://archinte.ama-assn.org/cgi/content/full/161/1/15>.
↑ “FASTSTATS – Deaths and Mortality”. Retrieved 2013-02-13.

Template:WikiDoc Sources CME Category::Cardiology

[pmid28800865-1] 1.0 ^1.1 LoVerde D, Iweala OI, Eginli A, Krishnaswamy G (2018). “Anaphylaxis”. Chest. 153 (2): 528–543. doi:10.1016/j.chest.2017.07.033. PMC 6026262. PMID 28800865.

[pmid24332862-2] Ma L, Danoff TM, Borish L (2014). “Case fatality and population mortality associated with anaphylaxis in the United States”. J Allergy Clin Immunol. 133 (4): 1075–83. doi:10.1016/j.jaci.2013.10.029. PMC 3972293. PMID 24332862.

[pmid17165265-3] Lieberman P, Camargo CA, Bohlke K, Jick H, Miller RL, Sheikh A; et al. (2006). “Epidemiology of anaphylaxis: findings of the American College of Allergy, Asthma and Immunology Epidemiology of Anaphylaxis Working Group”. Ann Allergy Asthma Immunol. 97 (5): 596–602. doi:10.1016/S1081-1206(10)61086-1. PMID 17165265.

[4] Neugut, Alfred, Anita Ghatak and Rachel Miller. “Anaphylaxis in the United States: An Investigation Into Its Epidemiology.” Arch Intern Med. 161.108 January 2001 15-21. 29 January 2007 <http://archinte.ama-assn.org/cgi/content/full/161/1/15>.

[urlFASTSTATS_-_Deaths_and_Mortality-5] “FASTSTATS – Deaths and Mortality”. Retrieved 2013-02-13.

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