Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Andersen-Tawil syndrome history and symptoms
Introduction
Overview
Overview
- The most common symptoms of Andersen-Tawil Syndrome include periodic paralysis, ventricular arrhythmias, syncope, muscular weakness, developmental abnormalities, sudden cardiac death and seizures.
History and Symptoms
History and Symptoms
History
Patients with Andersen-Tawil Syndrome may have a positive history of:
Common Symptoms
Common symptoms of Andersen-Tawil Syndrome include:[1][2]
- Periodic paralysis which are related to hypokalemia and are spontaneous in nature
- Ventricular arrhythmias
- Extrasystoles: Premature ventricular contraction
- Arrhythmic syncope
- Intermittent muscular weakness
- Skeletal developmental abnormalities
Less Common Symptoms
Less common symptoms of Andersen-Tawil Syndrome include:
- SCD(sudden cardiac death) is due to sudden hemodynamic collapse
- SCA: Spinocerebellar ataxia
- Generalized seizures, which are often misdiagnosed as primary seizure disorder
- Learning difficulties
References
References
- ↑ Tristani-Firouzi M, Jensen JL, Donaldson MR, Sansone V, Meola G, Hahn A; et al. (2002). “Functional and clinical characterization of KCNJ2 mutations associated with LQT7 (Andersen syndrome)”. J Clin Invest. 110 (3): 381–8. doi:10.1172/JCI15183. PMC 151085. PMID 12163457.
- ↑ Sansone V, Griggs RC, Meola G, Ptácek LJ, Barohn R, Iannaccone S; et al. (1997). “Andersen’s syndrome: a distinct periodic paralysis”. Ann Neurol. 42 (3): 305–12. doi:10.1002/ana.410420306. PMID 9307251.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Vamsikrishna Gunnam M.B.B.S [2]