Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Anembryonic gestation
Introduction
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Overview
Overview
An anembryonic gestation (aka blighted ovum) is a pregnancy in which a visible embryo never develops within a normal-appearing gestational sac, which likely occurs as a result of early embryonic death with continued development of the trophoblast. When small, the sac cannot be distinguished from the early normal pregnancy, as there may be a yolk sac, though a fetal pole is not seen.
This is one of the causes of miscarriage of a pregnancy.
For diagnosis, the sac must be of sufficient size that the absence of normal embryonic elements is established.
A pregnancy is anembryonic if a transvaginal ultrasound reveals a sac with a mean gestational sac diameter (MGD) greater than 13 mm and no yolk sac, or a MGD >18 mm with no embryo.
Many centers offer mothers a follow-up ultrasound 10 days later to verify diagnosis.
Several management options exist for anembryonic pregnancies which have not miscarried on their own.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]