Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Anemia of chronic disease future or investigational therapies
Introduction
Investigational Therapy:
- Use of agents that alter the function of hepcidin such as hepcidin antagonists.[1]
- Agents that alter the function of hepcidin receptor (ferroportin) in order to manage the level of hepcidin.[2]
References
- ↑ Fung E, Nemeth E (November 2013). “Manipulation of the hepcidin pathway for therapeutic purposes”. Haematologica. 98 (11): 1667–76. doi:10.3324/haematol.2013.084624. PMC 3815165. PMID 24186312.
- ↑ Poli M, Asperti M, Naggi A, Campostrini N, Girelli D, Corbella M, Benzi M, Besson-Fournier C, Coppin H, Maccarinelli F, Finazzi D, Arosio P (March 2014). “Glycol-split nonanticoagulant heparins are inhibitors of hepcidin expression in vitro and in vivo”. Blood. 123 (10): 1564–73. doi:10.1182/blood-2013-07-515221. PMC 3945865. PMID 24398330.