Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Anemia of chronic disease natural history, complications and prognosis
Introduction
Overview
Overview
Potentially life-threatening complications include congestive heart failure, Angina, arrhythmia, myocardial infarction and high-output heart failure. If left untreated, anemia of chronic disease usually manifests as congestive heart failure, angina, arrhythmia, myocardial infarction and high-output heart failure.The anemia will improve when the disease that is causing it is successfully treated.
Natural History
Natural History
If left untreated, anemia of chronic disease usually manifests as congestive heart failure, angina, arrhythmia, myocardial infarction and high-output heart failure.
Complications
Complications
Potentially life-threatening complications
- High-output heart failure
Decreased oxygen delivery[1]
- Exertional dyspnea Dyspnea at rest
- Fatigue Hyperdynamic signs like bounding pulses, palpitations, and a roaring pulsatile sound in the ears
- Lethargy, confusion
Hypovolemia
- Persistent hypotension Shock, and death
- Exacerbation of thrombocytopenic bleeding [2]
Prognosis
Prognosis
The anemia will improve when the disease that is causing it is successfully treated.
References
References
- ↑ Weiskopf RB, Viele MK, Feiner J, Kelley S, Lieberman J, Noorani M, Leung JM, Fisher DM, Murray WR, Toy P, Moore MA (January 1998). “Human cardiovascular and metabolic response to acute, severe isovolemic anemia”. JAMA. 279 (3): 217–21. PMID 9438742.
- ↑ Uhl L, Assmann SF, Hamza TH, Harrison RW, Gernsheimer T, Slichter SJ (September 2017). “Laboratory predictors of bleeding and the effect of platelet and RBC transfusions on bleeding outcomes in the PLADO trial”. Blood. 130 (10): 1247–1258. doi:10.1182/blood-2017-01-757930. PMC 5606003. PMID 28679741.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Omer Kamal, M.D.[2]