Health Dictionary
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Anglo-Scandinavian Cardiac Outcomes Trial
Introduction
Click here to download slides for ASCOT-LLA.
Overview
Overview
Hypertensive patients (n=10305) with total cholesterol < 251 mg/dL were randomly assigned to atorvastatin 10 mg daily and a significant reduction in non-fatal MI, fatal CHD and stoke (fatal and non-fatal) was noticed. No significant difference was observed on all-cause mortality. The trial was stopped earlier than expected of 5 years because of beneficial treatment[1].
References
References
- ↑ Sever PS, Dahlöf B, Poulter NR, Wedel H, Beevers G, Caulfield M; et al. (2003). “Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial–Lipid Lowering Arm (ASCOT-LLA): a multicentre randomised controlled trial”. Lancet. 361 (9364): 1149–58. doi:10.1016/S0140-6736(03)12948-0. PMID 12686036. Review in: ACP J Club. 2003 Nov-Dec;139(3):57
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]