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Anileridine

Introduction

Overview

Overview

Anileridine (trade name: Leritine) is a synthetic analgesic drug and is a member of the piperidine class of analgesic agents developed by Merck & Co. in the 1950s. It differs from pethidine (meperidine) in that the N-methyl group of meperidine is replaced by an N-aminophenethyl group, which increases its analgesic activity.

Anileridine is no longer manufactured in the US or Canada.[1]

Administration

Administration

As tablets or injection.[2]

Pharmacokinetics

Pharmacokinetics

Anileridine usually takes effect within 15 minutes of either oral or intravenous administration, and lasts 2–3 hours.[3] It is mostly metabolized by the liver.

References

References

  1. ↑ “Discontinued Prescription Drug Products”. Canadian Pharmacists’ Association. Retrieved 28 July 2008.
  2. ↑ “Pharmaceutical Information – LERITINE”. RxMed. Retrieved 16 June 2010.
  3. ↑ “Anileridine Consumer Information”. MedicineNet. Retrieved 28 July 2008.

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]