Anti-LKM antibody
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Overview
Anti-Liver Kidney Microsomal Antibodies (Anti-LKM antibody) are detected in serum of patients with different types of acute or chronic liver disease. These antibodies are targeted against cytochrome-P450 antigens. Three kind of Anti LKM is studied extensively-
| Microsomal Antibodies | Antigen | Disease |
|---|---|---|
| Anti-LKM 1 | Cytochrome P450 2D6 | Autoimmune Hepatitis type II and Chronic Hepatitis C(10%) |
| Anti-LKM 2 | Cytochrome P450 2C9 | Drug Induced Hepatitis(Tienilic acid induced) |
| Anti-LKM 3 | Cytochrome P450 1A2 | Chronic Hepatitis D |
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