Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Anti-NMDA receptor encephalitis laboratory findings
Introduction
Overview
Overview
In Anti-NMDA encephalitis, cerebrospinal fluid (CSF) analysis often shows mildly elevated white blood cell count, modestly increased protein levels, and the presence of oligoclonal bands. CSF-specific tests like IgG index and oligoclonal band tests can provide diagnostic value.
Laboratory Findings
Laboratory Findings
CSF Findings
- CSF white blood cells are frequently elevated in fewer than 200/mm3, and pleocytosis is commonly observed.
- Protein concentration is either normal or modestly elevated, and 60% of patients have CSF-specific oligoclonal bands.
- Immunoglobulin G (IgG) index and oligoclonal band tests are clinically relevant since they can be aberrant in normal CSF cell counts and protein levels.
References
References
- ↑ Dalmau J, Gleichman AJ, Hughes EG, Rossi JE, Peng X, Lai M; et al. (2008). “Anti-NMDA-receptor encephalitis: case series and analysis of the effects of antibodies”. Lancet Neurol. 7 (12): 1091–8. doi:10.1016/S1474-4422(08)70224-2. PMC 2607118. PMID 18851928.
- ↑ Titulaer MJ, McCracken L, Gabilondo I, Iizuka T, Kawachi I, Bataller L; et al. (2013). “Late-onset anti-NMDA receptor encephalitis”. Neurology. 81 (12): 1058–63. doi:10.1212/WNL.0b013e3182a4a49c. PMC 3795591. PMID 23946310.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] AE Dheeraj Makkar, M.D.[2]