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Anti-NMDA receptor encephalitis medical therapy

Introduction

Overview

Overview

The treatment of anti-NMDAR encephalitis involves immunotherapy, tumor diagnosis, and excision. Early immunotherapy has shown to improve outcomes. Treatment options include corticosteroids, plasmapheresis, immunoglobulins, and rituximab.

Medical Therapy

Medical Therapy

The treatment of anti-NMDAR encephalitis should include immunotherapy and the diagnosis and excision of the tumor. Β There is evidence that early immunotherapy may result in quicker recovery and decreased mortality.

Current immunotherapy includes corticosteroids, immune plasmapheresis, intravenous immunoglobulins, and rituximab.

References

References

[1] [2]

  1. ↑ Dalmau J, Gleichman AJ, Hughes EG, Rossi JE, Peng X, Lai M; et al. (2008). “Anti-NMDA-receptor encephalitis: case series and analysis of the effects of antibodies”. Lancet Neurol. 7 (12): 1091–8. doi:10.1016/S1474-4422(08)70224-2. PMCΒ 2607118. PMIDΒ 18851928.
  2. ↑ Titulaer MJ, McCracken L, Gabilondo I, Iizuka T, Kawachi I, Bataller L; et al. (2013). “Late-onset anti-NMDA receptor encephalitis”. Neurology. 81 (12): 1058–63. doi:10.1212/WNL.0b013e3182a4a49c. PMCΒ 3795591. PMIDΒ 23946310.

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] AE Dheeraj Makkar, M.D.[2]