Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Antiphospholipid syndrome risk factors
Introduction
Overview
Overview
The most common risk factors of antiphospholipid syndrome risk factors are history of autoimmune diseases like SLE, sjogren’s syndrome, infections- cytomegalovirus, human immunodeficiency virus, parvovirus B-19, hepatitis C virus, lyme’s disease, syphilis, E.coli, leptospirosis, medications such as hydralazine, quinidine, phenytoin, and amoxicillin, family history- antiphospholipid syndrome is common in patients with a family history of antiphospholipid syndrome.
Risk Factors
Risk Factors
The risk factors associated with antiphospholipid syndrome(APS) are as follows:[1][2][3][4][5]
Common risk factors
- Infections:
- Cytomegalovirus
- Human Immunodeficiency Virus
- Parvovirus B-19
- Hepatitis C Virus
- Lymes disease
- Syphilis
- E.coli
- Leptospirosis.
- Drugs:
- Family history: Antiphospholipid syndrome is common in patients with a family history of antiphospholipid syndrome.
Less common risk factors:
- Pregnancy
- Obesity
- Hypertension
- Sedentary lifestyle
- Recent surgery
- Tobacco Smoking
- Oral contraceptives
- Estrogen therapy
- Hyperlipidemias
- Cancer
References
References
- ↑ Ruiz-Irastorza G, Crowther M, Branch W, Khamashta MA (October 2010). “Antiphospholipid syndrome”. Lancet. 376 (9751): 1498–509. doi:10.1016/S0140-6736(10)60709-X. PMID 20822807.
- ↑ Willis R, Harris EN, Pierangeli SS (June 2012). “Pathogenesis of the antiphospholipid syndrome”. Semin. Thromb. Hemost. 38 (4): 305–21. doi:10.1055/s-0032-1311827. PMID 22510982.
- ↑ Gris JC, Brenner B (November 2013). “Antiphospholipid antibodies: neuropsychiatric presentations”. Semin. Thromb. Hemost. 39 (8): 935–42. doi:10.1055/s-0033-1357488. PMID 24129681.
- ↑ Koike T (October 2014). “My contribution, my dream – a look at the future of APS”. Lupus. 23 (12): 1332–4. doi:10.1177/0961203314534306. PMID 25228741.
- ↑ Sciascia S, Cuadrado MJ, Khamashta M, Roccatello D (May 2014). “Renal involvement in antiphospholipid syndrome”. Nat Rev Nephrol. 10 (5): 279–89. doi:10.1038/nrneph.2014.38. PMID 24642799.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Feham Tariq, MD [2]