Aortic stenosis historical perspective

Aortic stenosis was probably first described by Lazare Riviere, a French physician in 1663.

• In 1663, the earliest description of calcific aortic stenosis was made by a french physician named Lazare Rivière. He identified left ventricular hypertrophy and large caruncle-like masses obstructing the left ventricular outflow in an autopsy report from a patient with palpitations, progressive dyspnea, and loss of peripheral pulses.^[1][2]

• The first transcatheter aortic valve replacement procedure in the world was performed on 16 April 2002 in a 57-year-old inoperable patient with severe aortic stenosis. The procedure was done by the Interventional Cardiologist Professor Alain Cribier at the Charles Nicolle University Hospital in Rouen, France. ^{[3] [4]}

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