Aplastic anemia historical perspective

Paul Ehrlich in 1988 made known the notion of aplastic anemia. He narrated the case of a pregnant lady, who died of bone marrow failure. In1904 Anatole Chauffard named this disorder aplastic anemia. In 1920s and 1930s, Alice Hamilton and Harrison recognized bone marrow failure in workers who were exposed to benzene in the United States. In the late 1940s and early 1950s, an epidemic of aplastic anemia started showing up in people who were receiving chloramphenicol, and then aplastic anemia has been related to many classes of drugs generally used in medical practice. Neal Young from John Hopkins in 1980s introduced an immunosuppressive regimen which proved to be very effective treatment for aplastic anemia.

• Paul Ehrlich in 1988 made known the notion of aplastic anemia.
• He narrated the case of a pregnant lady, who died of bone marrow failure.
• In 1904, Anatole Chauffard named this disorder aplastic anemia.
• In 1920s and 1930s, Alice Hamilton and Harrison recognized bone marrow failure in workers who were exposed to benzene in the United States.
• In the late 1940s and early 1950s, an epidemic of aplastic anemia started showing up in people who were receiving chloramphenicol,
• Since late 60s, aplastic anemia has been related to many classes of drugs generally used in medical practice.
• Neal Young from John Hopkins in 1980s introduced an immunosuppressive regimen which proved to be very effective treatment for aplastic anemia.^[1]