Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Appendix cancer laboratory findings
Introduction
Overview
Overview
There are no diagnostic laboratory findings associated with appendix cancer in general. Laboratory findings consistent with the diagnosis of carcinoid tumors include , Chromogranin A (CgA), 5-HIAA (5-hydroxyindoleacetic acid) as well as Ki67. Some patients with colonic type adenocarcinoma may have elevated concentration of CEA and CA 19-9.
Laboratory Findings
Laboratory Findings
- There are no diagnostic laboratory findings associated with appendix cancer.
- Some patients with colonic type adenocarcinoma may have elevated concentration of CEA and CA 19-9.[1][2]
- Laboratory findings consistent with the diagnosis of carcinoid tumor include:
-
- The most specific marker of carcinoid tumors
- No clear correlation with symptoms
- Elevated concentration of 5-HIAA (usually suggestive of progression of carcinoid tumors)[4][5]
- Marker of cell proliferation
- Patients with values less than 2% seldom benefit from chemotherapy[6][4]
References
References
- ↑ Carmignani CP, Hampton R, Sugarbaker CE, Chang D, Sugarbaker PH (2004) Utility of CEA and CA 19-9 tumor markers in diagnosis and prognostic assessment of mucinous epithelial cancers of the appendix. J Surg Oncol 87 (4):162-6. DOI:10.1002/jso.20107 PMID: 15334630
- ↑ Oberg K, Janson ET, Eriksson B (1999) Tumour markers in neuroendocrine tumours. Ital J Gastroenterol Hepatol 31 Suppl 2 ():S160-2. PMID: 10604122
- ↑ Gut P, Czarnywojtek A, Fischbach J, BÄ…czyk M, Ziemnicka K, Wrotkowska E et al. (2016) Chromogranin A – unspecific neuroendocrine marker. Clinical utility and potential diagnostic pitfalls. Arch Med Sci 12 (1):1-9. DOI:10.5114/aoms.2016.57577 PMID: 26925113
- ↑ 4.0 4.1 Maroun J, Kocha W, Kvols L, Bjarnason G, Chen E, Germond C et al. (2006) Guidelines for the diagnosis and management of carcinoid tumours. Part 1: the gastrointestinal tract. A statement from a Canadian National Carcinoid Expert Group. Curr Oncol 13 (2):67-76. PMID: 17576444
- ↑ Eriksson B, Oberg K, Stridsberg M (2000) Tumor markers in neuroendocrine tumors. Digestion 62 Suppl 1 ():33-8. DOI:10.1159/000051853 PMID: 10940685
- ↑ Oberg K (2003) Diagnosis and treatment of carcinoid tumors. Expert Rev Anticancer Ther 3 (6):863-77. DOI:10.1586/14737140.3.6.863 PMID: 14686708
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Soroush Seifirad, M.D.[2]