Invasive pulmonary aspergillosis patients often appear sick-looking, lethargic, and fatigued. In contrast, patients with pulmonary aspergilloma, allergic bronchopulmonary aspergillosis, or allergic sinusitis often appear healthy. Physical examination of patients with pulmonary or invasive aspergillosis is usually remarkable for decreased breath sounds with wheezes, rales, and increased tactile fremitus. Physical examination of patients with cutaneous aspergillosis is usually remarkable for either single or multiple erythematous-to-violaceous cutaneous papules, macules, nodules, or plaques.^[1][2][3]

• Invasive pulmonary aspergillosis patients often appear sick-looking, lethargic, and fatigued
• Patients with pulmonary aspergilloma, allergic bronchopulmonary aspergillosis, or allergic sinusitis often appear healthy

• Fever
• Tachycardia
• Tachypnea
• Decreased oxygen saturation on room air

• Single or multiple erythematous-to-violaceous macules, papules, nodules, or plaques
• Pustules may be present among neonates
• Central necrotic ulcer

• Facial tenderness
• Excessive mucus secretion
• Nasal inflammation

• Rales
• Wheezes
• Increased tactile fremitus
• Increased vocal fremitus
• Decreased breath sounds
• Rhonchi

• Clubbing