Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Atrial septal defect ostium secundum pathophysiology
Introduction
Overview
Overview
Although atrial septal defect ostium secundum defects occur sporadically, they are associated with and occur with higher frequency in certain genetic disorders.
Pathophysiology
Pathophysiology
Associated Conditions
Most of ostium secundum ASDs occur sporadically. However, ostium secundum ASD has been found to occur with increased frequency in association with some genetic disorders including:
- Holt-Oram (heart-hand) syndrome
- Down syndrome
- Noonan syndrome
- Treacher Collins syndrome
- Thrombocytopenia-absent radii (TAR) syndrome
- Mitral valve prolapse: 10% to 20Â % of individuals with ostium secundum ASDs also have mitral valve prolapse.[1]
References
References
- ↑ Leachman R, Cokkinos D, Cooley D (1976). “Association of ostium secundum atrial septal defects with mitral valve prolapse”. Am J Cardiol. 38 (2): 167–9. PMID 952260.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]