Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Autoimmune hepatitis risk factors
Introduction
Overview
Overview
Common risk factors in the development of autoimmune hepatitis include female gender, Genetic predisposition associated with HLA-DR3 and HLA-DR4, and history of other autoimmune hepatitis eg thyroiditis, type 1 diabetes, ulcerative colitis, celiac disease, and rheumatoid arthritis.
Risk Factors
Risk Factors
Common Risk Factors
Common risk factors in the development of autoimmune hepatitis include:
- Females:
- Autoimmune hepatitis is more common in young females.
- Genetic predisposition:[1]
- History of another autoimmune disease:[2]
- Autoimmune diseases, including thyroiditis, type 1 diabetes, ulcerative colitis, celiac disease, and rheumatoid arthritis.
Less Common Risk Factors
Less common risk factors in the development of Autoimmune hepatitis include:
- A history of viral infections:[3][4]
- Autoimmune hepatitis is common who are infected with the measles, herpes simplex or epstein-Barr virus and hepatitis A, B or C infection in the past.
- History of drug intake:[5]
- minocycline, nitrofurantoin, hydralazine, methyldopa statins, fenofibrate, interferon, infliximab, etanercept increases the risk of autoimmune hepatitis.
References
References
- ↑ Donaldson PT (2004). “Genetics of autoimmune and viral liver diseases; understanding the issues”. J. Hepatol. 41 (2): 327–32. doi:10.1016/j.jhep.2004.06.001. PMID 15288484.
- ↑ “Autoimmune hepatitis – PubMed Health”. Retrieved 2013-01-02.
- ↑ Vento S, Cainelli F (2004). “Is there a role for viruses in triggering autoimmune hepatitis?”. Autoimmun Rev. 3 (1): 61–9. doi:10.1016/S1568-9972(03)00053-3. PMID 14871651.
- ↑ Huppertz HI, Treichel U, Gassel AM, Jeschke R, Meyer zum Büschenfelde KH (1995). “Autoimmune hepatitis following hepatitis A virus infection”. J. Hepatol. 23 (2): 204–8. PMID 7499793.
- ↑ Björnsson E, Talwalkar J, Treeprasertsuk S, Kamath PS, Takahashi N, Sanderson S, Neuhauser M, Lindor K (2010). “Drug-induced autoimmune hepatitis: clinical characteristics and prognosis”. Hepatology. 51 (6): 2040–8. doi:10.1002/hep.23588. PMID 20512992.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Manpreet Kaur, MD [2]