Autoimmune polyendocrine syndrome historical perspective

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Akshun Kalia M.B.B.S.[2]

Overview

In 19th century physicians first focussed their attention on constellation of symptoms associated with autoimmune polyendocrine syndrome. In 1855, Thomas Addison identified patients with Addison’s disease who also appeared to have coexisting pernicious anemia. In 1956, Roitt and Doniach found that patients with Hashimoto’s thyroiditis had circulating autoantibodies reacting with thyroid gland. In 1964, Carpenter described the association between adrenocortical failure, thyroiditis and insulin-dependent diabetes mellitus. In 1980, Neufeld and Blizzard first developed the classification for polyglandular failure and in 1982 categorized autoimmune polyendocrine syndrome into type 1 and type 2.

Historical Perspective

The history associated with autoimmune polyendocrine syndrome is as below:^[1]^[2]^[3]^[4]^[5]

In 19th century physicians first focussed their attention on constellation of symptoms associated with autoimmune polyendocrine syndrome.
In 1855, Thomas Addison identified patients with Addison’s disease who also appeared to have coexisting pernicious anemia.
In 1908, Claude and Gougerot described patients with Addison’s disease and pernicious anemia to have a common pathogenesis in their paper titled “Insufficence pluriglandulaire endocrinnienne”.
In 1926, Schmidt described the relationship between adrenocortical failure and thyroiditis.
In 1929, Thorpe and Handley first described the case of mucocutaneous candidiasis with glandular failure in a 4.5-year-old girl.
In 1956, Roitt and Doniach found that patients with Hashimoto’s thyroiditis had circulating autoantibodies reacting with thyroid gland.
In 1959, Beaven et al extensively reviewed relationship between Addison’s disease and diabetes mellitus.
In 1964, Carpenter described the association between adrenocortical failure, thyroiditis and insulin-dependent diabetes mellitus.
In 1974, Bottazzo and Doniach described autoantibodies against islet cells in patients with type 1A diabetes.
In 1980, Neufeld and Blizzard first developed the classification for polyglandular failure.
In 1981, Neufeld and colleagues categorized autoimmune polyendocrine syndrome into type 1 and type 2.

References

↑ SOLOMAN N, CARPENTER CJ, BENNETT IL, HARVEY AM (1965). “SCHMIDT’S SYNDROME (THYROID AND ADRENAL INSUFFICIENCY) AND COEXISTENT DIABETES MELLITUS”. Diabetes. 14: 300–4. PMID 14280372.
↑ Khalid, Nauman; Chhabra, Lovely; Ahmad, Sarah Aftab; Umer, Affan; Spodick, David H. (2015). “Autoimmune Polyglandular Syndrome Type 2 Complicated by Acute Adrenal Crisis and Pericardial Tamponade in the Setting of Normal Thyroid Function”. Methodist DeBakey Cardiovascular Journal. 11 (4): 250–252. doi:10.14797/mdcj-11-4-250. ISSN 1947-6094.
↑ Bottazzo GF, Florin-Christensen A, Doniach D (1974). “Islet-cell antibodies in diabetes mellitus with autoimmune polyendocrine deficiencies”. Lancet. 2 (7892): 1279–83. PMID 4139522.
↑ Betterle C, Dal Pra C, Mantero F, Zanchetta R (2002). “Autoimmune adrenal insufficiency and autoimmune polyendocrine syndromes: autoantibodies, autoantigens, and their applicability in diagnosis and disease prediction”. Endocr. Rev. 23 (3): 327–64. doi:10.1210/edrv.23.3.0466. PMID 12050123.
↑ “[POLYENDOCRINE insufficiency with normal hypophysis; Claude and Gougerot syndrome; primary panhypotelendocrinosis]”. Annee Endocrinol (in French). 11: 198–201. 1959. PMID 13856661.

Overview