
Health Dictionary
Reliable, easy-to-read patient information on common medical conditions β written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
BCL9L
Introduction
B-cell CLL/lymphoma 9 like is a protein that in humans is encoded by the BCL9L gene. [1]
Further reading
Further reading
- Sampietro J, Dahlberg CL, Cho US, Hinds TR, Kimelman D, Xu W (2006). “Crystal structure of a beta-catenin/BCL9/Tcf4 complex”. Mol. Cell. 24 (2): 293β300. doi:10.1016/j.molcel.2006.09.001. PMIDΒ 17052462.
- Miller TC, Rutherford TJ, Johnson CM, Fiedler M, Bienz M (2010). “Allosteric remodelling of the histone H3 binding pocket in the Pygo2 PHD finger triggered by its binding to the B9L/BCL9 co-factor”. J. Mol. Biol. 401 (5): 969β84. doi:10.1016/j.jmb.2010.07.007. PMCΒ 2927781. PMIDΒ 20637214.
- Brembeck FH, Wiese M, Zatula N, Grigoryan T, Dai Y, Fritzmann J, Birchmeier W (2011). “BCL9-2 promotes early stages of intestinal tumor progression”. Gastroenterology. 141 (4): 1359β70, 1370.e1β3. doi:10.1053/j.gastro.2011.06.039. PMIDΒ 21703997.
- Matsuura K, Jigami T, Taniue K, Morishita Y, Adachi S, Senda T, Nonaka A, Aburatani H, Nakamura T, Akiyama T (2011). “Identification of a link between Wnt/Ξ²-catenin signalling and the cell fusion pathway”. Nat Commun. 2: 548. doi:10.1038/ncomms1551. PMIDΒ 22109522.
- Zatula N, Wiese M, Bunzendahl J, Birchmeier W, Perske C, Bleckmann A, Brembeck FH (2014). “The BCL9-2 proto-oncogene governs estrogen receptor alpha expression in breast tumorigenesis”. Oncotarget. 5 (16): 6770β87. doi:10.18632/oncotarget.2252. PMCΒ 4196162. PMIDΒ 25149534.
- El-Hage P, Petitalot A, Monsoro-Burq AH, Maczkowiak F, Driouch K, Formstecher E, Camonis J, Sabbah M, BiΓ¨che I, Lidereau R, Lallemand F (2015). “The Tumor-Suppressor WWOX and HDAC3 Inhibit the Transcriptional Activity of the Ξ²-Catenin Coactivator BCL9-2 in Breast Cancer Cells”. Mol. Cancer Res. 13 (5): 902β12. doi:10.1158/1541-7786.MCR-14-0180. PMIDΒ 25678599.
