Developer site: The content shown here is test data.

MyEClinic
MyEClinic
Health Dictionary AI Health Chat Find an Online Doctor
A serene Zen garden with raked sand and smooth stones, symbolising clarity and calm

Health Dictionary

Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

Back to skin conditions

BMAL

Introduction

Bmal (brain and muscle aryl hydrocarbon receptor nuclear translocator (ARNT)-like) is a gene which encodes proteins regulating circadian rhythm. BMAL proteins form part of a basic-helix-loop-helix transcription factor. BMAL-1 dimerizes with CLOCK in vivo and transactivates gene expression of Period and Timeless in drosophila by binding to E-box elements in their promoters.[1] BMAL1-CLOCK also regulates Cryptochrome genes (e.g. Cry1, Cry2) and Period genes (e.g. Per1, Per2, Per3).[2] Bmal itself is downregulated by Period expression.

See also

See also

References

References

  1. ↑ Ishida N, Kaneko M, Allada R. Biological clocks. Proc Natl Acad Sci U S A. 1999 Aug 3;96(16):8819-20. [1]
  2. ↑ Edery I. Circadian rhythms in a nutshell. Physiol Genomics. 2000 Aug 9;3(2):59-74. [2]
External links

Template:WikiDoc Sources