BU-48
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Overview
BU-48 is a drug which is used in scientific research. It is from the oripavine family, related to better known drugs such as etorphine and buprenorphine.
Unlike most drugs from this family, BU-48 has only weak analgesic effects and acts primarily as a δ-opioid agonist. Its main effects are to produce convulsions,[1] but it may also have antidepressant effects.[2]
References
References
- ↑ Broom DC, Guo L, Coop A, Husbands S, Lewis JW, Woods JH, Traynor JR. BU48: A novel buprenorphine analogue that exhibits delta-opioid mediated convulsions but not delta-opioid mediated antinociception in mice. Journal of Pharmacology and Experimental Therapeutics 2000 Sep; 294(3): 1195–1200. PMID 10945877
- ↑ Broom DC, Jutkiewicz EM, Rice KC, Traynor JR, Woods JH. Behavioral effects of delta-opioid receptor agonists: potential antidepressants? Japanese Journal of Pharmacology. 2002 Sep;90(1):1-6. PMID 12396021
Looking for the patient version?
© 2026 MyEClinic – IFTM Institut für Telematik in der Medizin GmbH