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Barrett's esophagus future or investigational therapies

Introduction

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Overview

Overview

  • Biomarkers
  1. Can not be used to confirm the diagnosis of BarrettΒ΄s esophagus.
  2. Can not be used to predict risk of progression.
  3. Promising for the future[1].
  • Endoscopic Therapy
  1. In patients with confirmed high-grade dysplasia with Barrett’ esophagus, it is more recommended to proceed with endoscopic eradication therapy with radiofrequency ablation (RFA), photodynamic therapy (PDT), or endoscopic mucosal resection (EMR) rather than surveillance.
  2. In patients who have dysplasia in Barrett’s esophagus associated with a visible mucosal irregularity it is recommended to proceed with endoscopic mucosal resection (EMR) to determine the T stage of the neoplasia[1].
References

References

  1. ↑ 1.0 1.1 Spechler SJ, Sharma P, Souza RF, Inadomi JM, Shaheen NJ (2011). “American Gastroenterological Association medical position statement on the management of Barrett’s esophagus”. Gastroenterology. 140 (3): 1084–91. doi:10.1053/j.gastro.2011.01.030. PMIDΒ 21376940. Unknown parameter |month= ignored (help)