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Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

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Befuraline

Introduction

Befuraline is a piperazine derivative drug invented in Germany in the 1970s. [1] Befuraline has stimulant and antidepressant effects and has seen some use in Germany and France, although it has never become widely used. [2] Befuraline has an active metabolite benzylpiperazine, which is responsible for its stimulant effects.

File:Befuraline.png

1-(2-Benzofuranylcarbonyl)-4-benzylpiperazine

CAS# 41716-84-1; 41717-30-0

References

  1. ↑ Boksay IJ, Popendiker K, Weber RO, Soder A. Synthesis and pharmacological activity of befuraline (N-benzo[b]furan-2-ylcarbonyl-N’-benzylpiperazine), a new antidepressant compound. Arzneimittel-Forschung. 1979;29(2):193-204.
  2. ↑ Gastpar M, Gastpar G, Gilsdorf U. Befuraline, its safety and efficacy in depressed inpatients. Pharmacopsychiatry. 1985 Nov;18(6):351-5.

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