Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Benzylthiouracil
Introduction
Benzylthiouracil (BTU) is an antithyroid preparation. It is a thioamide, closely related to propylthiouracil.
Adverse effects
Adverse effects
Benzylthiouracil has been associated with severe adverse effects, notably vasculitis and subsequent ANCA-positive glomerulonephritis, as well as isolated reports of lung damage.[1][2][3][4]
References
References
- ↑ Tieulie N, Huong DL, Andreu M; et al. (2002). “[ANCA associated glomerulonephritis related to benzylthiouracil]”. Rev Med Interne (in French). 23 (10): 853–6. PMID 12428489.
- ↑ Kaaroud H, Khiari K, Ben Moussa F, Barbouch S, Boussema E, Ben Maïz H (2002). “[Vasculitis with renal and pulmonary involvement in a patient receiving benzylthiouracil for Graves disease]”. Rev Med Interne (in French). 23 (10): 857–61. PMID 12428490.
- ↑ Braham A, Houman MH, Rais L, Ben Gborbel I, Lamloum M, Miled M (2004). “[Benzylthiouracil induced ANCA-positive vasculitis]”. Presse médicale (in French). 33 (19 Pt 1): 1331–3. PMID 15615240.
- ↑ Thabet F, Sghiri R, Tabarki B, Ghedira I, Yacoub M, Essoussi AS (2006). “ANCA-associated diffuse alveolar hemorrhage due to benzylthiouracil”. Eur J Pediatr. 165 (7): 435–6. doi:10.1007/s00431-005-0053-4. PMID 16622664.