Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Beriberi laboratory findings
Introduction
Overview
Overview
The diagnosis of beriberi is assisted by a dietary history suggestive of a low thiamine intake and clinical manifestations. The most sensitive lab tests to detect thiamine deficiency are measurements of erythrocyte transketolase activity (ETKA) and the thiamine pyrophosphate effect (TPPE). Other tests include measurements of urinary concentrations of thiamine and its metabolites, as well as methylglyoxal.
Laboratory Findings
Laboratory Findings
- The diagnosis of beriberi is assisted by a dietary history suggestive of a low thiamine intake and clinical manifestations.
- However, objective biochemical tests of thiamine status may assist with diagnosis.[1]
- Measurement of erythrocyte transketolase activity (ETKA) and the thiamine pyrophosphate effect (TPPE) are sensitive tests for thiamine deficiency.
- Other tests include measurements of urinary concentrations of thiamine and its metabolites, as well as methylglyoxal.[2]
References
References
- ↑ Frank LL (2015). “Thiamin in Clinical Practice”. JPEN J Parenter Enteral Nutr. 39 (5): 503–20. doi:10.1177/0148607114565245. PMID 25564426.
- ↑ “StatPearls”. 2019. PMID 30725889.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Abdelrahman Ibrahim Abushouk, MD[2]