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Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

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Biliary cystadenoma and cystadenocarcinoma natural history, complications and prognosis

Introduction

Overview

Overview

Common complication of biliary cystadenoma include neoplastic transformation to biliary cystadenocarcinoma. Biliary cystadenoma with mesenchymal stroma is associated with most favorable prognosis.[1]

Complications

Complications

  • In fact, even if the cystadenoma is a benign neoplasm, it has a high rate of recurrence and a potential for neoplastic transformation.
  • Malignant transformation rate can be as high as 30%.[2]
Prognosis

Prognosis

Although biliary cystadenomas are benign tumors, they may recur after excision and have potential to develop into biliary cystadenocarcinomas.[3]

Biliary cystadenoma

  • The prognosis of completely removed billiary cystadenomas is excellent, recurrence is rare.[4]
  • Cystadenomas with mesenchymal stroma are considered premalignant with a good prognosis while those without are known to transform to malignancy more often with a poor prognosis.[1]

Biliary cystadenocarcinoma

  • When treated with radical excision biliary cystadenocarcinomas have good prognosis, particularly those with mesenchymal stroma, unless the tumor invades the adjacent liver tissue or neighboring organs, or metastases are present.[4]
  • Biliary cystadenocarcinomas in men which are not associated with mesenchymal stroma have worse prognosis, even after complete excision.[4]
References

References

  1. ↑ 1.0 1.1 Ahanatha Pillai, Sastha; Velayutham, Vimalraj; Perumal, Senthilkumar; Ulagendra Perumal, Srinivasan; Lakshmanan, Anand; Ramaswami, Sukumar; Ramasamy, Ravi; Sathyanesan, Jeswanth; Palaniappan, Ravichandran; Rajagopal, Surendran (2012). “Biliary Cystadenomas: A Case for Complete Resection”. HPB Surgery. 2012: 1–6. doi:10.1155/2012/501705. ISSN 0894-8569.
  2. ↑ Ramacciato, Giovanni; Nigri, Giuseppe R; D’Angelo, Francesco; Aurello, Paolo; Bellagamba, Riccardo; Colarossi, Cristina; Pilozzi, Emanuela; Del Gaudio, Massimo (2006). World Journal of Surgical Oncology. 4 (1): 76. doi:10.1186/1477-7819-4-76. ISSN 1477-7819. Missing or empty |title= (help)
  3. ↑ Biliary cystadenoma.Dr Yuranga Weerakkody and Radswiki et al.Radiopaedia.org 2015. http://radiopaedia.org/articles/biliary-cystadenoma
  4. ↑ 4.0 4.1 4.2 Chandrasekar, G. (2015), Biliary Cystadenoma of Liver. (PDF), Chennai: Stanley Medical Journal, p. 37-42, retrieved December 10, 2015

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Suveenkrishna Pothuru, M.B,B.S. [2]