Biliary dyskinesia natural history, complications and prognosis

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Shakiba Hassanzadeh, MD [2]

Overview

Symptoms of biliary dyskinesia have been reported to resolve without any invasive procedure in about half of the patients. Patients with gallbladder dyskinesia (GD) that have typical classic biliary symptoms are more likely to have improvement after cholecystectomy compared to those with atypical symptoms. Relief of symptoms has been reported in 80% of the patients that were diagnosed with sphincter of Oddi disorder (SOD) by manometry and treated with sphincterotomy.

Natural History and Prognosis

Natural History

Symptoms of biliary dyskinesia have been reported to resolve without any invasive procedure in about half of the patients.^[1]

Prognosis

Patients with gallbladder dyskinesia (GD) that have typical classic biliary symptoms are more likely to have improvement after cholecystectomy compared to those with atypical symptoms.^[2]
Relief of symptoms has been reported in 80% of the patients that were diagnosed with sphincter of Oddi disorder (SOD) by manometry and treated with sphincterotomy.^[3]

References

↑ Bielefeldt K, Saligram S, Zickmund SL, Dudekula A, Olyaee M, Yadav D (2014). “Cholecystectomy for biliary dyskinesia: how did we get there?”. Dig Dis Sci. 59 (12): 2850–63. doi:10.1007/s10620-014-3342-9. PMID 25193389.
↑ Carr JA, Walls J, Bryan LJ, Snider DL (2009). “The treatment of gallbladder dyskinesia based upon symptoms: results of a 2-year, prospective, nonrandomized, concurrent cohort study”. Surg Laparosc Endosc Percutan Tech. 19 (3): 222–6. doi:10.1097/SLE.0b013e3181a74690. PMID 19542850.
↑ Toouli J (2002). “Biliary Dyskinesia”. Curr Treat Options Gastroenterol. 5 (4): 285–291. doi:10.1007/s11938-002-0051-9. PMID 12095476.

[pmid25193389-1] Bielefeldt K, Saligram S, Zickmund SL, Dudekula A, Olyaee M, Yadav D (2014). “Cholecystectomy for biliary dyskinesia: how did we get there?”. Dig Dis Sci. 59 (12): 2850–63. doi:10.1007/s10620-014-3342-9. PMID 25193389.

[pmid19542850-2] Carr JA, Walls J, Bryan LJ, Snider DL (2009). “The treatment of gallbladder dyskinesia based upon symptoms: results of a 2-year, prospective, nonrandomized, concurrent cohort study”. Surg Laparosc Endosc Percutan Tech. 19 (3): 222–6. doi:10.1097/SLE.0b013e3181a74690. PMID 19542850.

[pmid12095476-3] Toouli J (2002). “Biliary Dyskinesia”. Curr Treat Options Gastroenterol. 5 (4): 285–291. doi:10.1007/s11938-002-0051-9. PMID 12095476.

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