Bladder cancer historical perspective

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Farima Kahe M.D. [2]

Overview

Association between bladder cancer and environmental carcinogens is first discovered in 1895. First cystectomy is performed as a treatment for bladder cancer in in 1877. Radium is first used as a treatment of bladder tumors in 1903. Neoadjuvant chemotherapy including methotrexate, vinblastine, doxorubicin, and cisplatin (MVAC) is first described in 1985. FDA approved the use of live bacterium, Bacillus Calmette-Guérin (BCG) for treatment and prevent the recurrence of superficial tumors in 1990.

Historical Perspective

Discovery

Cystoscope was first discovered by Maximilian Nitze, a German urologist, in 1877.^[1]
Association between bladder cancer and environmental carcinogens is first discovered in 1895.
Urine cytology is first described in 1945.^[2]
Micropapillary bladder cancer is first described in 1982.^[3]
Approximately 356,000 new bladder cancer cases of bladder cancer are reported in 2002 worldwide.^[4]

Landmark Events in the Development of Treatment Strategies

First cystectomy is performed as a treatment for bladder cancer in in 1877.
Radium is first used as a treatment of bladder tumors in 1903.^[5]
Early bladder removal surgery includes removing the bladder (cystectomy) and surrounding tissue where cancer is most likely to spread is performed in 1956.^[6]
FDA approves the first chemotherapy drug cisplatin for treatment of bladder tumors in 1978.
Reconstructive bladder surgery in introduced in 1980-1985.
Neoadjuvant chemotherapy including methotrexate, vinblastine, doxorubicin, and cisplatin (MVAC) is first described in 1985.^[7]
Intravesical chemotherapy using mitomycin to reduce risk of bladder cancer’s recurrence is discovered in 1988.^[8]
FDA approved the use of live bacterium, bacillus Calmette-Guérin (BCG) for treatment and prevent the recurrence of superficial tumors in 1990.^[9]
New chemotherapy combination regimen including gemcitabine with cisplatin is introduced as more effective with less side effects compare to MVAC therapy in 2000.^[10]
New technology that helps to detect cancerous tumors in the bladder that are invisible to the naked eye is discovered in 2016.

References

↑ Wood JW, Casiano RR (2012). “Inverted papillomas and benign nonneoplastic lesions of the nasal cavity”. Am J Rhinol Allergy. 26 (2): 157–63. doi:10.2500/ajra.2012.26.3732. PMC 3906506. PMID 22487294.
↑ Griffiths, T. R. L. (2013). “Current perspectives in bladder cancer management”. International Journal of Clinical Practice. 67 (5): 435–448. doi:10.1111/ijcp.12075. ISSN 1368-5031.
↑ Heudel, Pierre; El Karak, Fadi; Ismaili, Nabil; Droz, Jean-Pierre; Flechon, Aude (2009). “Micropapillary bladder cancer: a review of Léon Bérard Cancer Center experience”. BMC Urology. 9 (1). doi:10.1186/1471-2490-9-5. ISSN 1471-2490.
↑ Ploeg M, Aben KK, Kiemeney LA (June 2009). “The present and future burden of urinary bladder cancer in the world”. World J Urol. 27 (3): 289–93. doi:10.1007/s00345-009-0383-3. PMC 2694323. PMID 19219610.
↑ LENZ M, CAHILL GF (October 1947). “The treatment of cancer of the bladder by radium needles”. Am J Roentgenol Radium Ther. 58 (4): 486–92. PMID 20273482.
↑ Balar A, Bajorin DF, Milowsky MI (June 2011). “Management of invasive bladder cancer in patients who are not candidates for or decline cystectomy”. Ther Adv Urol. 3 (3): 107–17. doi:10.1177/1756287211407543. PMC 3159398. PMID 21904567.
↑ Sagaster P, Flamm J, Flamm M, Mayer A, Donner G, Oberleitner S, Havelec L, Lepsinger L, Ludwig H (July 1996). “Neoadjuvant chemotherapy (MVAC) in locally invasive bladder cancer”. Eur. J. Cancer. 32A (8): 1320–4. PMID 8869093.
↑ Porten SP, Leapman MS, Greene KL (2015). “Intravesical chemotherapy in non-muscle-invasive bladder cancer”. Indian J Urol. 31 (4): 297–303. doi:10.4103/0970-1591.166446. PMC 4626913. PMID 26604440.
↑ Askeland EJ, Newton MR, O’Donnell MA, Luo Y (2012). “Bladder Cancer Immunotherapy: BCG and Beyond”. Adv Urol. 2012: 181987. doi:10.1155/2012/181987. PMC 3388311. PMID 22778725.
↑ Als AB, Sengelov L, Von Der Maase H (2008). “Gemcitabine and cisplatin in locally advanced and metastatic bladder cancer; 3- or 4-week schedule?”. Acta Oncol. 47 (1): 110–9. doi:10.1080/02841860701499382. PMID 17851853.

[pmid22487294-1] Wood JW, Casiano RR (2012). “Inverted papillomas and benign nonneoplastic lesions of the nasal cavity”. Am J Rhinol Allergy. 26 (2): 157–63. doi:10.2500/ajra.2012.26.3732. PMC 3906506. PMID 22487294.

[Griffiths2013-2] Griffiths, T. R. L. (2013). “Current perspectives in bladder cancer management”. International Journal of Clinical Practice. 67 (5): 435–448. doi:10.1111/ijcp.12075. ISSN 1368-5031.

[HeudelEl_Karak2009-3] Heudel, Pierre; El Karak, Fadi; Ismaili, Nabil; Droz, Jean-Pierre; Flechon, Aude (2009). “Micropapillary bladder cancer: a review of Léon Bérard Cancer Center experience”. BMC Urology. 9 (1). doi:10.1186/1471-2490-9-5. ISSN 1471-2490.

[pmid19219610-4] Ploeg M, Aben KK, Kiemeney LA (June 2009). “The present and future burden of urinary bladder cancer in the world”. World J Urol. 27 (3): 289–93. doi:10.1007/s00345-009-0383-3. PMC 2694323. PMID 19219610.

[pmid20273482-5] LENZ M, CAHILL GF (October 1947). “The treatment of cancer of the bladder by radium needles”. Am J Roentgenol Radium Ther. 58 (4): 486–92. PMID 20273482.

[pmid21904567-6] Balar A, Bajorin DF, Milowsky MI (June 2011). “Management of invasive bladder cancer in patients who are not candidates for or decline cystectomy”. Ther Adv Urol. 3 (3): 107–17. doi:10.1177/1756287211407543. PMC 3159398. PMID 21904567.

[pmid8869093-7] Sagaster P, Flamm J, Flamm M, Mayer A, Donner G, Oberleitner S, Havelec L, Lepsinger L, Ludwig H (July 1996). “Neoadjuvant chemotherapy (MVAC) in locally invasive bladder cancer”. Eur. J. Cancer. 32A (8): 1320–4. PMID 8869093.

[pmid26604440-8] Porten SP, Leapman MS, Greene KL (2015). “Intravesical chemotherapy in non-muscle-invasive bladder cancer”. Indian J Urol. 31 (4): 297–303. doi:10.4103/0970-1591.166446. PMC 4626913. PMID 26604440.

[pmid22778725-9] Askeland EJ, Newton MR, O’Donnell MA, Luo Y (2012). “Bladder Cancer Immunotherapy: BCG and Beyond”. Adv Urol. 2012: 181987. doi:10.1155/2012/181987. PMC 3388311. PMID 22778725.

[pmid17851853-10] Als AB, Sengelov L, Von Der Maase H (2008). “Gemcitabine and cisplatin in locally advanced and metastatic bladder cancer; 3- or 4-week schedule?”. Acta Oncol. 47 (1): 110–9. doi:10.1080/02841860701499382. PMID 17851853.

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